Systems biology approaches based discovery of a small molecule inhibitor targeting both c-Met/PARP-1 and inducing cell death in breast cancer.

Breast cancer is the second most common types of cancer worldwide. Molecular strategies have developed rapidly; however, novel treatments strategies with high efficacy and lower toxicity are still urgently demanded.

Notably, biological networks estimated from microarraydata and functional activity network analysis could be utilized to identify and validate potential targets. In this study, two microarraydata (GSE13477, GSE31192) were firstly selected, and analyzed by multi-functional activity network analysis to generate the core protein-protein-interaction (PPI) network.

Several potential targets were subsequently identified and c-Met and poly (ADP-ribose) polymerase-1 (PARP-1) were manually chosen as the key targets in breast cancer. Furthermore, virtual screening and molecular dynamics (MD) simulations were utilized to recognize novel c-Met/PARP-1 inhibitors in Specs products database.

Three small molecules, namely, ZINC19909930, ZINC20032678 and ZINC13562414 were selected. Additionally, these compounds were synthesized, and two breast cancer cell lines, MDA-MB-231 and MCF-7 cells were used to validate our bioinformatic findings in vitro. MTT assay and Hoechst staining showed that ZINC20032678 significantly induced breast cancer cell death, which was mediated through apoptosis by flow cytometry.

Furthermore, ZINC20032678 was shown to target the active sites of the both targets and recruitment of downstream apoptotic signaling pathways, eventually inducing breast cancer cell apoptosis.

AES-350

T9041-10mg 10mg Ask for price
Description: AES-350

AES-350

T9041-1g 1g Ask for price
Description: AES-350

AES-350

T9041-1mg 1mg Ask for price
Description: AES-350

AES-350

T9041-50mg 50mg Ask for price
Description: AES-350

AES-350

T9041-5mg 5mg Ask for price
Description: AES-350

AES-135

T10255-10mg 10mg Ask for price
Description: AES-135

AES-135

T10255-1g 1g Ask for price
Description: AES-135

AES-135

T10255-1mg 1mg Ask for price
Description: AES-135

AES-135

T10255-50mg 50mg Ask for price
Description: AES-135

AES-135

T10255-5mg 5mg Ask for price
Description: AES-135

AES-135

MBS3843544-10mg 10mg
EUR 810

AES-135

MBS3843544-50mg 50mg
EUR 2370

AES-135

MBS3843544-5mg 5mg
EUR 465

AES-135

MBS3843544-5x50mg 5x50mg
EUR 10655

AES-135

MBS5764581-10mg 10mg
EUR 625

AES-135

MBS5764581-1mg 1mg
EUR 245

AES-135

MBS5764581-25mg 25mg
EUR 1160

AES-135

MBS5764581-50mg 50mg
EUR 1845

AES-135

MBS5764581-5mg 5mg
EUR 395

AES-350

MBS5765163-10mg 10mg
EUR 540

AES-350

MBS5765163-1mg 1mg
EUR 225

AES-350

MBS5765163-25mg 25mg
EUR 965

AES-350

MBS5765163-50mg 50mg
EUR 1445

AES-350

MBS5765163-5mg 5mg
EUR 350

AES siRNA

20-abx900213
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

AES siRNA

20-abx906940
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

AES siRNA

20-abx906941
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

AES Peptide

3607P 0.05 mg
EUR 197.7
Description: (CT) AES peptide

AES Peptide

3609P 0.05 mg
EUR 197.7
Description: (NT) AES peptide

AES Peptide

42-365P 0.1 mg
EUR 405.6
Description: (NT) AES Peptide

AES Protein

20-abx262697
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 ug
  • 1 mg
  • 2 µg

AES Peptide

MBS152200-005mg 0.05mg
EUR 175

AES Peptide

MBS152200-5x005mg 5x0.05mg
EUR 770

AES Peptide

MBS152745-005mg 0.05mg
EUR 175

AES Peptide

MBS152745-5x005mg 5x0.05mg
EUR 770

AES Peptide

MBS3228155-01mg 0.1mg
EUR 180

AES Peptide

MBS3228155-5x01mg 5x0.1mg
EUR 730

AES Antibody

24349 100ul
EUR 479

AES Antibody

24349-100ul 100ul
EUR 468

AES Antibody

24350 100ul
EUR 479

AES Antibody

24350-100ul 100ul
EUR 468

AES Antibody

3607-002mg 0.02 mg
EUR 206.18
Description: AES Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis. It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family. Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

AES Antibody

3607-01mg 0.1 mg
EUR 523.7
Description: AES Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis. It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family. Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

AES Antibody

3609-002mg 0.02 mg
EUR 206.18
Description: AES Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis. It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family. Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

AES Antibody

3609-01mg 0.1 mg
EUR 523.7
Description: AES Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis. It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family. Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

AES Antibody

36095 100ul
EUR 319

AES Antibody

36095-100ul 100ul
EUR 302.4

AES Antibody

1-CSB-PA973928
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against AES. Recognizes AES from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

AES Antibody

E036095 100μg/100μl
EUR 255
Description: Available in various conjugation types.

AES Antibody

E97874 100ul
EUR 255
Description: Available in various conjugation types.

AES antibody

70R-1059 100 ug
EUR 407
Description: Rabbit polyclonal AES antibody raised against the C terminal of AES

AES antibody

70R-7912 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal AES antibody

AES Antibody

1-CSB-PA551903
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against AES. Recognizes AES from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

AES Antibody

1-CSB-PA001405ESR2HU
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against AES. Recognizes AES from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

AES Antibody

GWB-2710F9 0.1 mg Ask for price

AES Antibody

GWB-ML300C 50ug Ask for price

AES Antibody

R35917-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Amino-terminal enhancer of split, AES-1

AES Antibody

MBS7124696-005mL 0.05mL
EUR 190

AES Antibody

MBS7124696-01mL 0.1mL
EUR 270

AES Antibody

MBS7124696-5x01mL 5x0.1mL
EUR 1205

AES Antibody

MBS7124697-005mL 0.05mL
EUR 190

AES Antibody

MBS7124697-01mL 0.1mL
EUR 270

AES Antibody

MBS7124697-5x01mL 5x0.1mL
EUR 1205

AES Antibody

MBS9412814-01mL 0.1mL
EUR 495

AES Antibody

MBS9412814-5x01mL 5x0.1mL
EUR 2075

AES Antibody

MBS9403841-01mL 0.1mL
EUR 305

AES Antibody

MBS9403841-5x01mL 5x0.1mL
EUR 1230

AES Antibody

MBS9407608-01mL 0.1mL
EUR 495

AES Antibody

MBS9407608-5x01mL 5x0.1mL
EUR 2075

AES Antibody

MBS150869-01mg 0.1mg
EUR 445

AES Antibody

MBS150869-5x01mg 5x0.1mg
EUR 1965

AES Antibody

MBS150968-01mg 0.1mg
EUR 445

AES Antibody

MBS150968-5x01mg 5x0.1mg
EUR 1965

AES Antibody

MBS1491947-005mL 0.05mL
EUR 190

AES Antibody

MBS1491947-01mL 0.1mL
EUR 270

AES Antibody

MBS1491947-5x01mL 5x0.1mL
EUR 1205

AES Antibody

C42512-100ul 100μl
EUR 217
Description: AES Rabbit Polyclonal Antibody

AES Antibody

C42512-50ul 50μl
EUR 143.5
Description: AES Rabbit Polyclonal Antibody

AES siRNA (Rat)

MBS8212765-15nmol 15nmol
EUR 405

AES siRNA (Rat)

MBS8212765-30nmol 30nmol
EUR 565

AES siRNA (Rat)

MBS8212765-5x30nmol 5x30nmol
EUR 2450

AES Rabbit pAb

A7874-100ul 100 ul
EUR 369.6

AES Rabbit pAb

A7874-200ul 200 ul
EUR 550.8

AES Rabbit pAb

A7874-20ul 20 ul
EUR 219.6

AES Rabbit pAb

A7874-50ul 50 ul
EUR 267.6

AES Rabbit pAb

E2507874 100ul
EUR 225
Description: Available in various conjugation types.

AES Rabbit pAb

MBS8547098-01mL 0.1mL
EUR 305

AES Rabbit pAb

MBS8547098-01mLAF405L 0.1mL(AF405L)
EUR 565

AES Rabbit pAb

MBS8547098-01mLAF405S 0.1mL(AF405S)
EUR 565

AES Rabbit pAb

MBS8547098-01mLAF610 0.1mL(AF610)
EUR 565

AES Rabbit pAb

MBS8547098-01mLAF635 0.1mL(AF635)
EUR 565

AES Rabbit pAb

A7874 50μL
EUR 152.33

AES siRNA (Mouse)

MBS8200177-15nmol 15nmol
EUR 405

AES siRNA (Mouse)

MBS8200177-30nmol 30nmol
EUR 565

AES siRNA (Mouse)

MBS8200177-5x30nmol 5x30nmol
EUR 2450

AES siRNA (Human)

MBS8223619-15nmol 15nmol
EUR 405

AES siRNA (Human)

MBS8223619-30nmol 30nmol
EUR 565

AES siRNA (Human)

MBS8223619-5x30nmol 5x30nmol
EUR 2450

AES Blocking Peptide

33R-3414 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of AES antibody, catalog no. 70R-1059

AES Blocking Peptide

33R-3767 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of AES antibody, catalog no. 70R-7912

AES Immunizing Peptide

MBS427550-01mg 0.1mg
EUR 225

AES Polyclonal Antibody

ABP57720-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AES from Human, Mouse, Rat. This AES antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AES protein

AES Polyclonal Antibody

ABP57720-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AES from Human, Mouse, Rat. This AES antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AES protein

AES Polyclonal Antibody

ABP57720-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AES from Human, Mouse, Rat. This AES antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human AES protein

AES Polyclonal Antibody

E11-202046 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Polyclonal AES Antibody

AMM08746G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AES . This antibody is tested and proven to work in the following applications:

Polyclonal AES Antibody

AMM08747G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AES . This antibody is tested and proven to work in the following applications:

AES Conjugated Antibody

C36095 100ul
EUR 476.4

AES Polyclonal Antibody

A73477 50 μl
EUR 557

AES Polyclonal Antibody

BT-AP14139-100ul 100ul Ask for price
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho| a protein involved in neurogenesis during embryonic development. The encoded protein| which belongs to the groucho/TLE family of proteins| can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

AES Polyclonal Antibody

BT-AP14139-20ul 20ul Ask for price
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho| a protein involved in neurogenesis during embryonic development. The encoded protein| which belongs to the groucho/TLE family of proteins| can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

AES Polyclonal Antibody

BT-AP14139-50ul 50ul Ask for price
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho| a protein involved in neurogenesis during embryonic development. The encoded protein| which belongs to the groucho/TLE family of proteins| can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

AES Polyclonal Antibody

E44H09653 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

AES Polyclonal Antibody

E-AB-62616-120uL 120uL
EUR 320
Description: Unconjugated

AES Polyclonal Antibody

E-AB-62616-200uL 200uL
EUR 530
Description: Unconjugated

AES Polyclonal Antibody

E-AB-62616-60uL 60uL
EUR 200
Description: Unconjugated

AES Polyclonal Antibody

E-AB-62616-each each Ask for price
Description: Unconjugated

AES Polyclonal Antibody

MBS9128149-002mL 0.02mL
EUR 200

AES Polyclonal Antibody

MBS9128149-005mL 0.05mL
EUR 255

AES Polyclonal Antibody

MBS9128149-01mL 0.1mL
EUR 345

AES Polyclonal Antibody

MBS9128149-02mL 0.2mL
EUR 545

AES Polyclonal Antibody

MBS9128149-5x02mL 5x0.2mL
EUR 2265

AES Polyclonal Antibody

MBS8531400-01mg 0.1mg
EUR 305

AES Polyclonal Antibody

MBS8531400-01mLAF405L 0.1mL(AF405L)
EUR 465

AES Polyclonal Antibody

MBS8531400-01mLAF405S 0.1mL(AF405S)
EUR 465

AES Polyclonal Antibody

MBS8531400-01mLAF610 0.1mL(AF610)
EUR 465

AES Polyclonal Antibody

MBS8531400-01mLAF635 0.1mL(AF635)
EUR 465

AES Polyclonal Antibody

MBS2520981-002mL 0.02mL
EUR 140

AES Polyclonal Antibody

MBS2520981-006mL 0.06mL
EUR 180

AES Polyclonal Antibody

MBS2520981-012mL 0.12mL
EUR 260

AES Polyclonal Antibody

MBS2520981-02mL 0.2mL
EUR 405

AES Polyclonal Antibody

MBS2541137-006mL 0.06mL
EUR 190

AES Polyclonal Antibody

MBS2541137-012mL 0.12mL
EUR 265

AES Polyclonal Antibody

MBS2541137-02mL 0.2mL
EUR 415

AES Polyclonal Antibody

MBS2541137-5x02mL 5x0.2mL
EUR 1835

AES Polyclonal Antibody

MBS2527642-002mL 0.02mL
EUR 140

AES Polyclonal Antibody

MBS2527642-006mL 0.06mL
EUR 180

AES Polyclonal Antibody

MBS2527642-012mL 0.12mL
EUR 260

AES Polyclonal Antibody

MBS2527642-02mL 0.2mL
EUR 405

AES Conjugated Antibody

MBS9446558-01mLAF350 0.1mL(AF350)
EUR 480

AES Conjugated Antibody

MBS9446558-01mLAF405 0.1mL(AF405)
EUR 480

AES Conjugated Antibody

MBS9446558-01mLAF488 0.1mL(AF488)
EUR 480

AES Conjugated Antibody

MBS9446558-01mLAF555 0.1mL(AF555)
EUR 480

AES Conjugated Antibody

MBS9446558-01mLBiotin 0.1mL(Biotin)
EUR 480

AES Polyclonal Antibody

RD84769A-120uL 120μL
EUR 360
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

AES Polyclonal Antibody

RD84769A-200uL 200μL
EUR 630
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

AES Polyclonal Antibody

RD84769A-60uL 60μL
EUR 204
Description: The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

Compound 0120-0020

T131683-10mg 10mg Ask for price
Description: Compound 0120-0020

Compound 0120-0020

T131683-1g 1g Ask for price
Description: Compound 0120-0020

Compound 0120-0020

T131683-1mg 1mg Ask for price
Description: Compound 0120-0020

Compound 0120-0020

T131683-50mg 50mg Ask for price
Description: Compound 0120-0020

Compound 0120-0020

T131683-5mg 5mg Ask for price
Description: Compound 0120-0020

Compound 0120-0018

T131684-10mg 10mg Ask for price
Description: Compound 0120-0018

Compound 0120-0018

T131684-1g 1g Ask for price
Description: Compound 0120-0018

Compound 0120-0018

T131684-1mg 1mg Ask for price
Description: Compound 0120-0018

Compound 0120-0018

T131684-50mg 50mg Ask for price
Description: Compound 0120-0018

Compound 0120-0018

T131684-5mg 5mg Ask for price
Description: Compound 0120-0018

Compound N060-0120

T131220-10mg 10mg Ask for price
Description: Compound N060-0120

Compound N060-0120

T131220-1g 1g Ask for price
Description: Compound N060-0120

Compound N060-0120

T131220-1mg 1mg Ask for price
Description: Compound N060-0120

Compound N060-0120

T131220-50mg 50mg Ask for price
Description: Compound N060-0120

Compound N060-0120

T131220-5mg 5mg Ask for price
Description: Compound N060-0120

Compound N060-0120

MBS5796158-INQUIRE INQUIRE Ask for price

Compound 0120-0020

MBS5796615-INQUIRE INQUIRE Ask for price

Compound 0120-0018

MBS5796616-INQUIRE INQUIRE Ask for price

Aes (untagged) - Mouse amino-terminal enhancer of split (Aes), (10ug)

MC208598 10 µg Ask for price

Rat Aes ELISA Kit

ELI-49545r 96tests
EUR 756

Rat Aes ELISA Kit

EF018323 96tests
EUR 566

AES protein (His tag)

80R-1712 50 ug
EUR 307
Description: Purified recombinant Human AES protein

Mouse Aes ELISA Kit

EF014197 96tests
EUR 566

Human AES ELISA KIT

EF004609 96tests
EUR 566

Rat AES shRNA Plasmid

20-abx985519
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

AES Antibody (C-term)

GWB-486C80 0.1 mg Ask for price

AES Antibody (C-term)

GWB-C4A3C5 0.05 mg Ask for price

AES Antibody (C-term)

MBS9210382-008mL 0.08mL
EUR 210

AES Antibody (C-term)

MBS9210382-04mL 0.4mL
EUR 430

AES Antibody (C-term)

MBS9210382-5x04mL 5x0.4mL
EUR 1910

Mouse AES shRNA Plasmid

20-abx970657
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Human AES shRNA Plasmid

20-abx950120
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Human AES Protein Lysate

MBS136968-002mg 0.02mg
EUR 365

Human AES Protein Lysate

MBS136968-5x002mg 5x0.02mg
EUR 1410

AES Peptide - middle region

MBS3225900-01mg 0.1mg
EUR 180

AES Peptide - middle region

MBS3225900-5x01mg 5x0.1mg
EUR 730

Aes (GFP-tagged) - Mouse amino-terminal enhancer of split (Aes), (10ug)

MG217929 10 µg Ask for price

AES antibody - middle region

MBS3200862-01mL 0.1mL
EUR 455

AES antibody - middle region

MBS3200862-5x01mL 5x0.1mL
EUR 1995

AES, CT (Amino Enhancer of Split, Amino-terminal Enhancer of Split, AES 1, AES-1, AES 2, AES-2, Esp1, Gp130-associated Protein GAM, Groucho Homolog, GRG, GRG Protein, GRG5, Protein ESP1, TLE5)

MBS6010945-01mg 0.1(mg
EUR 590

AES, CT (Amino Enhancer of Split, Amino-terminal Enhancer of Split, AES 1, AES-1, AES 2, AES-2, Esp1, Gp130-associated Protein GAM, Groucho Homolog, GRG, GRG Protein, GRG5, Protein ESP1, TLE5)

MBS6010945-5x01mg 5x0.1mg
EUR 2505

Aes (Myc-DDK-tagged) - Mouse amino-terminal enhancer of split (Aes)

MR217929 10 µg Ask for price

OPPA00098-2UG - AES Protein

OPPA00098-2UG 2ug
EUR 70

Collectively, our findings not only offer systems biology approaches based drug target identification, but also provide the new clues for developing novel inhibitors for future breast cancer research.